Vitamin D Status in Term Newborn at King Abdulaziz University, Jeddah, Saudi Arabia

Authors

  • Nadia M. Fida King Abdulaziz University

DOI:

https://doi.org/10.4197/med.14-2.6

Keywords:

Vitamin D, Cord blood, Newborn, 25-hydroxyvitamin D, Vitamin D deficiency

Abstract

Vitamin D is required for normal bone growth and mineralization. The aim was to determine the prevalence of hypovitaminosis D in full-term newborns. Serum calcium, inorganic phosphorus, 25 (OH) vitamins D (25OHD), alkaline phosphatase, parathyroid hormone levels were studied in 41 cord blood of full-term newborns. According to 25OHD levels in cord blood, the newborns were divided into three groups: Group I [25OHD <25 nmol/L, n=2], Group II [25OHD (25-50 nmol/L) n=9] and Group III [25OHD > 50 nmol/L, n=30]. There was no significant difference in the demographic characteristics between the three groups. 25OHD level declined significantly in Group I compared to Groups II and III with (p<0.01, p<0.000) and in Group II compared to Group III (p<0.000). Meanwhile, calcium in Group II declined considerably compared to Group III with (p<0.05). In all newborn, there was a significant positive correlation between creatinine and albumin (r=0.359, p<0.05) and inorganic phosphorus (r=0.324, p<0.05) and a negative correlation between calcium and parathyroid hormone (r=-0.396, p<0.01). We observed high prevalence of physiologically significant hypovitaminosis D among full-term newborns, the magnitude of which warrants further research.

Author Biography

Nadia M. Fida, King Abdulaziz University

Department of Pediatrics

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Published

2007-04-01

How to Cite

Fida, N. M. (2007). Vitamin D Status in Term Newborn at King Abdulaziz University, Jeddah, Saudi Arabia. Journal of King Abdulaziz University - Medical Sciences, 14(2), 61–71. https://doi.org/10.4197/med.14-2.6

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Section

Articles