A Clinical and Pathological Study of Kikuchi–Fujimoto Disease in A University Hospital in Saudi Arabia

  • Fahad A. Alghamdi King Abdulaziz University, Jeddah, Saudi Arabia
  • Mohammed S. Abdelwahed University of Jeddah, Jeddah, Saudi Arabia; Alazhar University, Cairo, Egypt
  • Abdulaziz Alghamdi King Abdulaziz University, Jeddah, Saudi Arabia
  • Hani z. Marzouki King Abdulaziz University, Jeddah, Saudi Arabia
  • Ghadeer A. Mokhtar King Abdulaziz University, Jeddah, Saudi Arabia
  • Shadi S. Alkhayyat King Abdulaziz University, Jeddah, Saudi Arabia
Keywords: Kikuchi–Fujimoto disease; Histiocytic necrotizing lymphadenitis

Abstract

Kikuchi–Fujimoto disease is a benign disease of self-limiting course characterized by lymphadenopathy that is often mistaken clinically as lymphoma or infectious lymphadenitis. To prevent such a mistake, a clinical and pathological correlation is recommended. In this retrospective study, we are documenting the clinical and pathological features of this disease through the last 15 years (2001-2016) in King Abdulaziz University Hospital; and comparing results with that of international findings. From a total number of 1805 lymph nodes sent for histopathological examination during that period, only 9 cases had been diagnosed as Kikuchi–Fujimoto disease. Three (33%) cases were 20 years old and under; five (56%) cases were in the ages between 20 to 40 years old and only one (11%) was above 40 years old. Eight (89%) cases were females. Regarding the outcome, all cases showed complete recovery and there was no recurrence. Only two histological phases were seen, namely proliferative and necrotizing phases.

 

Author Biographies

Fahad A. Alghamdi, King Abdulaziz University, Jeddah, Saudi Arabia

Department of Pathology, Faculty of Medicine

 

Mohammed S. Abdelwahed, University of Jeddah, Jeddah, Saudi Arabia; Alazhar University, Cairo, Egypt

Department of Pathology, Faculty of Medicine

Department of Pathology, Faculty of Medicine

 

Abdulaziz Alghamdi, King Abdulaziz University, Jeddah, Saudi Arabia

Faculty of Dentistry

 

Hani z. Marzouki, King Abdulaziz University, Jeddah, Saudi Arabia

Department of Otolaryngology - Head and Neck Surgery, Faculty of Medicine

 

Ghadeer A. Mokhtar, King Abdulaziz University, Jeddah, Saudi Arabia

Department of Pathology, Faculty of Medicine

 

Shadi S. Alkhayyat, King Abdulaziz University, Jeddah, Saudi Arabia

Department of Medicine, Faculty of Medicine

 

Published
2018-04-01
How to Cite
Alghamdi, F., Abdelwahed, M., Alghamdi, A., Marzouki, H., Mokhtar, G., & Alkhayyat, S. (2018). A Clinical and Pathological Study of Kikuchi–Fujimoto Disease in A University Hospital in Saudi Arabia. Journal of King Abdulaziz University - Medical Sciences, 25(1), 23-29. Retrieved from http://jkaumedsci.org.sa/index.php/jkaumedsci/article/view/551
Section
Articles