Vaginal Colonization by Escherichia coli in Pregnant Women at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

  • Taghreed J. Jamal King Abdulaziz University
  • Hassan El-Banna A. Younus Menoufiya University
  • Hassan S. Abduljabbar King Abdulaziz University
  • Asif A. Jiman-Fatani King Abdulaziz University
  • Amal F. Makled Menoufiya University
Keywords: Escherichia coli K1 strains; Vaginal colonization; Pregnant women; Saudi Arabia

Abstract

Maternal and neonatal infections by Escherichia coli remain a challenging problem for obstetricians and pediatricians. This study aims to determine the prevalence of vaginal colonization by Escherichia coli among pregnant women attending the Antenatal Clinics at King Abdulaziz University Hospital in Jeddah- Saudi Arabia, and to investigate the susceptibility of isolated Escherichia coli to the most commonly used antimicrobials. In this study, 100 pregnant women in the last trimester and 25 non-pregnant women were screened for vaginal colonization of Escherichia coli. The suspected colonies were identified by conventional methods and were confirmed by automated technology "Vitek 2 System". Also, antimicrobial susceptibility tests were done by the same methods". Escherichia coli isolates were serotyped to detect the presence of K1 antigen. Out of 100 pregnant women in the last trimester; twenty-one (21%) were Escherichia coli positive. Also, out of 25 non-pregnant women; four (16%) were Escherichia coli-positive. All of the isolated Escherichia coli were susceptible to most antimicrobial agents. The percentage of vaginal Escherichia coli resistance to trimethoprim/sulfamethoxazole, ampicillin and piperacillin ranged from 38.1% to 42.9%. The virulence factor K1 antigen was demonstrated in 42.9% of Escherichia coli -positive pregnant women.

Author Biographies

Taghreed J. Jamal, King Abdulaziz University

Department of Biology, Faculty of Science

Hassan El-Banna A. Younus, Menoufiya University

Department of Microbiology and Immunology, Faculty of Medicine

Hassan S. Abduljabbar, King Abdulaziz University

Department of Obstetrics and Gynecology, Faculty of Medicine

Asif A. Jiman-Fatani, King Abdulaziz University

Department of Medical Microbiology and Parasitology, Faculty of Medicine, and Clinical and Molecular
Microbiology Laboratories

Amal F. Makled, Menoufiya University

Department of Microbiology and Immunology, Faculty of Medicine

Published
2017-09-30
How to Cite
Jamal, T. J., Younus, H. E.-B. A., Abduljabbar, H. S., Jiman-Fatani, A. A., & Makled, A. F. (2017). Vaginal Colonization by Escherichia coli in Pregnant Women at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Journal of King Abdulaziz University - Medical Sciences, 24(3), 39-49. https://doi.org/10.4197/Med.24-3.4
Section
Articles

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